SCHEMBL26547342

SCHEMBL26547342

N#Cc1cccc(S(=O)(=O)N2C[C@H](N3CCCC(F)(F)C3)C[C@H]2C(=O)NC(Cc2ccc(NC(=O)c3c(Cl)cncc3Cl)cc2)C(=O)O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ITGA4 P13612 20/20 1.00
ITGB1 P05556 12/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30076410 1.00 ITGA4 (1.00) ITGA4ITGB1
SCHEMBL2881869 1.00 ITGA4 (1.00) ITGA4ITGB1
SCHEMBL8268137 0.96 ITGA4 (1.00) ITGA4ITGB1
SCHEMBL2881521 0.95 ITGA4 (1.00) ITGA4ITGB1
SCHEMBL4398861 0.94 ITGA4 (1.00) ITGA4ITGB1
SCHEMBL4398870 0.94 ITGA4 (1.00) ITGA4ITGB1
SCHEMBL2881921 0.93 ITGA4 (1.00) ITGA4ITGB1
SCHEMBL13197848 0.93 ITGA4 (0.86) ITGA4ITGB1
SCHEMBL2882022 0.93 ITGA4 (0.86) ITGA4ITGB1
SCHEMBL5987573 0.92 ITGA4 (1.00) ITGA4ITGB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023196342-A1 α4β1/7 INTEGRIN LIGAND CONJUGATED COMPOUNDS AND USES THEREOF ADARX PHARMACEUTICALS, INC. (US) 2023-10-12 WO disclosed