Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.47 |
| ▸ | PDE2A | O00408 | 3/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31321940 | 0.93 | S1PR1 (0.51) | S1PR1S1PR3FFAR4FFAR1PPARG | |
| SCHEMBL19358277 | 0.84 | TRIM24 (0.53) | FFAR4FFAR1PDE3BPDE3APDE2A | |
| SCHEMBL23804143 | 0.83 | MCL1 (0.58) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL116455 | 0.83 | FFAR4 (0.62) | FFAR4FFAR1CYP2C9SCN5A | |
| SCHEMBL1626220 | 0.83 | TDP1 (0.48) | S1PR1S1PR3 | |
| SCHEMBL29700092 | 0.83 | FFAR4 (0.62) | FFAR4FFAR1CYP2C9SCN5A | |
| SCHEMBL2332483 | 0.82 | PDE3B (0.47) | FFAR4FFAR1PDE3BPDE3APDE2A | |
| SCHEMBL2325134 | 0.81 | PDE3B (0.46) | FFAR4FFAR1PDE3BPDE3APDE2A | |
| SCHEMBL30983963 | 0.80 | TDP1 (0.46) | S1PR1S1PR3 | |
| SCHEMBL1124419 | 0.80 | ALDH1A1 (0.58) | S1PR1FFAR4FFAR1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585517-A1 | USE OF SUBSTITUTED 2-PHENYLBENZIMIDAZOLES AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004062663-A1 | USE OF SUBSTITUTED 2-PHENYLBENZIMIDAZOLES AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-07-29 | — | — | WO | disclosed |