Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22275519 | 0.78 | DUT (0.30) | DUT | |
| SCHEMBL2647273 | 0.74 | — | — | |
| SCHEMBL24915169 | 0.70 | DUT (0.33) | DUT | |
| SCHEMBL22275492 | 0.69 | DUT (0.32) | DUT | |
| Hydrochloric Acid SCHEMBL4467770 | 0.68 | MEN1 (0.30) | — | |
| SCHEMBL22275273 | 0.68 | — | — | |
| SCHEMBL22275464 | 0.68 | — | — | |
| SCHEMBL30079830 | 0.66 | BACE1 (0.37) | DUT | |
| SCHEMBL4785374 | 0.66 | — | — | |
| SCHEMBL17398411 | 0.65 | DUT (0.34) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150983-A1 | TRIAZOLO-PYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LTD. (GB) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000047582-A1 | TRIAZOLO-PYRIDAZINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 2000-08-17 | — | — | WO | disclosed |