SCHEMBL9576396

SCHEMBL9576396

CC(C)C(O)CC=CC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
GABRR1 P24046 2/20 0.41
GABRR2 P28476 2/20 0.41
BLM P54132 2/20 0.41
GABRR3 A8MPY1 1/20 0.41
LMNA P02545 1/20 0.41
APEX1 P27695 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
GABRP O00591 2/20 0.38
GABRD O14764 2/20 0.38
GABRA1 P14867 2/20 0.38
GABRB1 P18505 2/20 0.38
GABRG2 P18507 2/20 0.38
GABRB3 P28472 2/20 0.38
GABRA5 P31644 2/20 0.38
GABRA3 P34903 2/20 0.38
GABRA2 P47869 2/20 0.38
GABRB2 P47870 2/20 0.38
GABRA4 P48169 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL453106 0.81
SCHEMBL265515 0.81
SCHEMBL11465249 0.81
SCHEMBL7391129 0.80 TSHR (0.39) TSHRGABRR1GABRR2BLMGABRR3
SCHEMBL5972994 0.80 TSHR (0.39) TSHRGABRR1GABRR2BLMGABRR3
SCHEMBL22793359 0.80 ALDH1A1 (0.40) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL12973059 0.78
SCHEMBL15352 0.78
SCHEMBL15353 0.78
SCHEMBL14497821 0.77 TSHR (0.41) TSHRGABRR1GABRR2BLMGABRR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5225483-A THERMOPLASTIC COMPOSITION OF POLYPROPYLENE AND STYRENE COPOLYMER RESINS EXXON CHEMICAL PATENTS INC. (US) 1993-07-06 US disclosed
WO-1993002135-A1 IMPROVED THERMOPLASTIC COMPOSITION OF POLYPROPYLENE AND STYRENE COPOLYMER RESINS EXXON CHEMICAL PATENTS INC. (US) 1993-02-04 WO disclosed
WO-1993002136-A2 THERMOPLASTIC COMPOSITION CONTAINING A STYRENE RESIN EXXON CHEMICAL PATENTS INC. (US) 1993-02-04 WO disclosed
US-5153282-A Preparation of polyolefin incorporating functional groups from masked functional group-containing monomers EXXON CHEMICAL PATENTS INC. (US) 1992-10-06 US disclosed
EP-0295076-B1 POLYOLEFINS INCORPORATING FUNCTIONAL GROUPS, MASKED FUNCTIONAL GROUP-CONTAINING MONOMERS, REACTION MIXTURES, AND METHODS FOR PREPARING SAME EXXON CHEMICAL PATENTS INC. (US) 1992-09-30 EP disclosed
US-4987200-A METALLIZATION BEFORE POLYMERIZATION EXXON CHEMICAL PATENTS INC. (US) 1991-01-22 US disclosed
EP-0375200-A2 Functionalized alpha-olefin copolymers having narrow molecular weight distribution EXXON CHEMICAL PATENTS INC. (US) 1990-06-27 EP disclosed
WO-1990006327-A1 FUNCTIONALIZED ALPHA-OLEFIN COPOLYMERS HAVING NARROW MOLECULAR WEIGHT DISTRIBUTION EXXON CHEMICAL PATENTS INC. (US) 1990-06-14 WO disclosed
EP-0366412-A2 Graft polymers of functionalized ethylene-alpha-olefin copolymer with polypropylene, methods of preparation, and use in polypropylene compositions EXXON CHEMICAL PATENTS INC. (US) 1990-05-02 EP disclosed
EP-0295076-A1 Polyolefins incorporating functional groups, masked functional group-containing monomers, reaction mixtures, and methods for preparing same EXXON CHEMICAL PATENTS INC. (US) 1988-12-14 EP disclosed