Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SPNS2 | Q8IVW8 | 2/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25400068 | 0.99 | TLR8 (0.51) | TLR8HTR2AMEN1KMT2AKDM4E | |
| SCHEMBL26553787 | 0.97 | TLR8 (0.55) | TLR8HTR2AMEN1KMT2AKDM4E | |
| SCHEMBL24095153 | 0.95 | MEN1 (0.51) | TLR8MEN1KMT2AKDM4EMAPT | |
| SCHEMBL26553784 | 0.93 | HTR2A (0.51) | TLR8HTR2AMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL25398676 | 0.92 | HTR2A (0.50) | TLR8HTR2AMEN1KMT2AKDM4E | |
| SCHEMBL26553781 | 0.90 | MEN1 (0.56) | TLR8HTR2AMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL25402084 | 0.88 | MEN1 (0.54) | TLR8HTR2AMEN1KMT2ASPNS2 | |
| SCHEMBL29437090 | 0.87 | MEN1 (0.56) | TLR8HTR2AMEN1KMT2AKDM4E | |
| SCHEMBL26553782 | 0.87 | MEN1 (0.56) | TLR8HTR2AMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL25438479 | 0.86 | MEN1 (0.54) | TLR8HTR2AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331683-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331683-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | SPNS2, SPCS2, SMN1; SMN2 | TLR8 4824/4885HTR2A 1201/4885MEN1 3339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.