⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26558131 | 0.95 | — | — | |
| SCHEMBL26558079 | 0.94 | — | — | |
| SCHEMBL26557819 | 0.90 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL26558184 | 0.84 | ALDH1A1 (0.32) | — | |
| SCHEMBL26558081 | 0.84 | — | — | |
| SCHEMBL26558086 | 0.82 | — | — | |
| SCHEMBL26565858 | 0.82 | — | — | |
| SCHEMBL26558087 | 0.82 | TOP2A (0.37) | — | |
| SCHEMBL26558089 | 0.81 | — | — | |
| SCHEMBL26242236 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | Atea Pharmaceuticals, Inc. (US) | 2023-10-19 | — | — | US | disclosed |