Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13079015 | 0.98 | DNM1 (0.48) | DNM1CA12CA1CA2CA9 | |
| SCHEMBL11528947 | 0.93 | DNM1 (0.35) | DNM1OPRM1CA12CA1CA2 | |
| SCHEMBL22388655 | 0.93 | DNM1 (0.35) | DNM1OPRM1CA12CA1CA2 | |
| SCHEMBL24093996 | 0.91 | DNM1 (0.44) | DNM1OPRM1CA12CA1CA2 | |
| SCHEMBL5539887 | 0.88 | DNM1 (0.48) | DNM1OPRM1CA12CA1CA2 | |
| SCHEMBL5544687 | 0.88 | DNM1 (0.48) | DNM1OPRM1CA12CA1CA2 | |
| SCHEMBL28601890 | 0.88 | DNM1 (0.48) | DNM1OPRM1CA12CA1CA2 | |
| SCHEMBL1728456 | 0.88 | DNM1 (0.48) | DNM1OPRM1CA12CA1CA2 | |
| SCHEMBL5544717 | 0.88 | DNM1 (0.48) | DNM1OPRM1CA12CA1CA2 | |
| SCHEMBL10674908 | 0.88 | DNM1 (0.48) | DNM1OPRM1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205074-A1 | PROCESSES AND INTERMEDIATES FOR SYNTHESIS OF ADAGRASIB | Mirati Therapeutics, Inc. (US) | 2023-10-26 | — | — | WO | disclosed |
| US-20230333477-A1 | METHOD OF MANUFACTURING A SEMICONDUCTOR DEVICE | TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) | 2023-10-19 | — | — | US | disclosed |