Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 10/20 | 0.50 |
| ▸ | SUV39H1 | O43463 | 2/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26557865 | 0.88 | PRKDC (0.52) | PRKDCSUV39H1PRMT1SMYD3PDE3A | |
| SCHEMBL21664419 | 0.86 | ENPP1 (0.49) | PRKDCSUV39H1PRMT1SMYD3PDE3A | |
| SCHEMBL26557373 | 0.79 | NAMPT (0.45) | PRKDCPDE3AENPP1JAK2JAK3 | |
| SCHEMBL21664273 | 0.78 | ENPP1 (0.49) | PRKDCPDE3AENPP1JAK2JAK3 | |
| SCHEMBL21664414 | 0.77 | ENPP1 (0.48) | PRKDCSUV39H1PRMT1SMYD3ENPP1 | |
| SCHEMBL2923361 | 0.76 | CLK4 (0.54) | SUV39H1PRMT1SMYD3ENPP1KDM4E | |
| SCHEMBL694440 | 0.76 | PDGFRB (0.45) | SUV39H1PRMT1SMYD3KDM4EPABPC1 | |
| SCHEMBL21456810 | 0.76 | ENPP1 (0.47) | PRKDCSUV39H1PRMT1SMYD3PDE3A | |
| SCHEMBL2070213 | 0.76 | BPTF (0.49) | KDM4EHSD17B10 | |
| SCHEMBL26564079 | 0.75 | PRKDC (0.44) | PRKDCSUV39H1PRMT1SMYD3PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3551188-B1 | SUBSTITUTED QUINAZOLINE SULFONAMIDES AS THIOREDOXIN INTERACTING PROTEIN (TXNIP) INHIBITORS | SOUTHERN RES INST (US) | 2023-10-18 | — | — | EP | disclosed |