Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 10/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17672370 | 0.80 | ATM (0.34) | ATM | |
| SCHEMBL1329486 | 0.79 | RECQL (0.43) | PDK2 | |
| SCHEMBL16411910 | 0.78 | PDK2 (0.39) | PDK2 | |
| SCHEMBL15448158 | 0.76 | SMN1; SMN2 (0.35) | PDK2ATM | |
| SCHEMBL24928163 | 0.76 | S1PR5 (0.35) | PDK2ATM | |
| SCHEMBL16979516 | 0.76 | S1PR5 (0.35) | PDK2ATM | |
| SCHEMBL3964578 | 0.75 | BCHE (0.36) | ATM | |
| SCHEMBL17913806 | 0.74 | SLC6A2 (0.48) | — | |
| SCHEMBL3709106 | 0.73 | ATM (0.42) | ATM | |
| SCHEMBL29965898 | 0.72 | SMN1; SMN2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173745-A2 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | Array Biopharma, Inc. (US) | 2010-04-14 | — | — | EP | disclosed |
| WO-2008118718-A2 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC. (US) | 2008-10-02 | — | — | WO | disclosed |