SCHEMBL26562232

SCHEMBL26562232

CC(=O)NC1C(OC2C(O)C(O)[C@H](CO)O[C@@H]2OC2C(O)C(COC(O)C(OC3OC(CO)C(O[C@H](O)C[C@@H](O)C(O)CO[C@]4(C(=O)NCCOCCOCCOCCN)C[C@@H](O)C(NC(C)=O)C(O)(CO)O4)C(O)C3NC(C)=O)C(O)C(O)C(C)CO)OC(OC3C(CO)OC4OC(C)=NC4C3O)C2O)OC(CO)C(OC2OC(CO[C@]3(C(=O)NCCOCCOCCOCCN)C[C@@H](O)C(NC(C)=O)C(C(O)O)O3)C(O)C(O)C2O)C1O

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ MAG P20916 11/20 0.37
▸ SIGLEC7 Q9Y286 6/20 0.34
▸ SELE P16581 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26562428 0.77 SIGLEC7 (0.38) MAGSIGLEC7SELE
SCHEMBL24191630 0.74 SIGLEC7 (0.55) MAGSIGLEC7SELE
SCHEMBL24191529 0.74 SIGLEC7 (0.55) MAGSIGLEC7SELE
SCHEMBL26562047 0.73 SIGLEC7 (0.53) MAGSIGLEC7SELE
SCHEMBL26562151 0.72 MAG (0.43) MAGSIGLEC7SELE
SCHEMBL26554524 0.72 SIGLEC7 (0.49) MAGSIGLEC7SELE
SCHEMBL26554564 0.72 SIGLEC7 (0.53) MAGSIGLEC7SELE
SCHEMBL17447128 0.65 SIGLEC7 (0.49) MAGSIGLEC7SELE
SCHEMBL26554496 0.64 SIGLEC7 (0.54) MAGSIGLEC7SELE
SCHEMBL17448433 0.62 SIGLEC7 (0.42) MAGSIGLEC7SELE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230330248-A1 ANTIBODY-DRUG CONJUGATE INCLUDING NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2023-10-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230330248-A1 ANTIBODY-DRUG CONJUGATE INCLUDING NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE STING1, CGAS, TLR9 MAG 1875/4885SIGLEC7 141/4885SELE 2211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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