SCHEMBL26562428

SCHEMBL26562428

CC(=O)NC1C(CC2C(OCC3OC(OC4C(CO)OC5OC(C)=NC5C4O)C(O)C(O[C@H]4O[C@@H](CO)C(O)C(O)C4OC4OC(CO)C(OC5OC(CO[C@]6(C(=O)NCCOCCOCCOCCN)C[C@@H](O)C(NC(C)=O)C(C(O)O)O6)C(O)C(O)C5O)C(O)C4NC(C)=O)C3O)OC(CO)C(O)C2O)OC(CO)C(O[C@H]2C[C@@H](O)C(O)C(CO)O2)C1O

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ SIGLEC7 Q9Y286 6/20 0.38
▸ MAG P20916 11/20 0.37
▸ ENGASE Q8NFI3 1/20 0.35
▸ SELE P16581 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26554564 0.85 SIGLEC7 (0.53) SIGLEC7MAGSELE
SCHEMBL24191529 0.82 SIGLEC7 (0.55) SIGLEC7MAGSELE
SCHEMBL24191630 0.82 SIGLEC7 (0.55) SIGLEC7MAGSELE
SCHEMBL26554524 0.81 SIGLEC7 (0.49) SIGLEC7MAGSELE
SCHEMBL26562232 0.77 MAG (0.37) SIGLEC7MAGSELE
SCHEMBL19726164 0.72 SIGLEC7 (0.58) SIGLEC7MAGSELE
SCHEMBL17447128 0.72 SIGLEC7 (0.49) SIGLEC7MAGSELE
SCHEMBL26554536 0.72 SIGLEC7 (0.61) SIGLEC7MAGSELE
SCHEMBL26554496 0.71 SIGLEC7 (0.54) SIGLEC7MAGSELE
SCHEMBL30540287 0.71 SIGLEC7 (0.48) SIGLEC7MAGENGASE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230330248-A1 ANTIBODY-DRUG CONJUGATE INCLUDING NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2023-10-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230330248-A1 ANTIBODY-DRUG CONJUGATE INCLUDING NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE STING1, CGAS, TLR9 SIGLEC7 141/4885MAG 1875/4885ENGASE 91/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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