Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 9/20 | 0.68 |
| ▸ | TAS1R1 | Q7RTX1 | 9/20 | 0.68 |
| ▸ | TAS1R2 | Q8TE23 | 6/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26564754 | 0.88 | TAS1R3 (0.71) | TAS1R3TAS1R1TAS1R2ALDH1A1HSD17B10 | |
| SCHEMBL704675 | 0.81 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1HSD17B10 | |
| SCHEMBL704676 | 0.81 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1HSD17B10 | |
| SCHEMBL26564758 | 0.79 | TAS1R3 (0.58) | TAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL12521450 | 0.77 | TAS1R3 (0.74) | TAS1R3TAS1R1TAS1R2ALDH1A1HSD17B10 | |
| SCHEMBL26564759 | 0.76 | TAS1R3 (0.68) | TAS1R3TAS1R1TAS1R2ALDH1A1HSD17B10 | |
| SCHEMBL702372 | 0.76 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL702373 | 0.76 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL702688 | 0.73 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1MEN1 | |
| SCHEMBL4277918 | 0.73 | TAS1R3 (0.63) | TAS1R3TAS1R1TAS1R2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331663-A1 | SMALL MOLECULE NICOTINAMIDE ADENINE DINUCLEOTIDE MODULATORS | THE CLEVELAND CLINIC FOUNDATION | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331663-A1 | SMALL MOLECULE NICOTINAMIDE ADENINE DINUCLEOTIDE MODULATORS | NQO1, NADK, CD38 | TAS1R3 4637/4885TAS1R1 4099/4885TAS1R2 3830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.