Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | ARG1 | P05089 | 1/20 | 0.36 |
| ▸ | ARG2 | P78540 | 1/20 | 0.36 |
| ▸ | PEPD | P12955 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4440592 | 0.84 | ATM (0.59) | ATMDPP4PREPFAPDPP8 | |
| SCHEMBL4440586 | 0.84 | ATM (0.59) | ATMDPP4PREPFAPDPP8 | |
| SCHEMBL8342634 | 0.84 | ATM (0.59) | ATMDPP4PREPFAPDPP8 | |
| SCHEMBL7379942 | 0.79 | ACE (0.49) | ATMACE | |
| SCHEMBL5087041 | 0.79 | ATM (0.52) | ATMCTSKCTSSPEPDACE | |
| SCHEMBL6126706 | 0.79 | ATM (0.52) | ATMCTSKCTSSPEPDACE | |
| SCHEMBL26980896 | 0.79 | ATM (0.52) | ATMCTSKCTSSPEPDACE | |
| SCHEMBL26118721 | 0.79 | ATM (0.52) | ATMCTSKCTSSPEPDACE | |
| SCHEMBL26980895 | 0.79 | ATM (0.52) | ATMCTSKCTSSPEPDACE | |
| SCHEMBL24054658 | 0.78 | ATM (0.53) | ATMDPP4PREPFAPDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |