Sugi Predict

Sugi Predict / Compounds / SCHEMBL5087041

SCHEMBL5087041

SCHEMBL5087041

C[C@@H]1C[C@@H](C(=O)O)N(C(=O)O)C1

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ATM Q13315 1/20 0.52
▸ CTSK P43235 2/20 0.34
▸ PEPD P12955 1/20 0.34
▸ CTSS P25774 1/20 0.33
▸ ACE P12821 3/20 0.32
▸ PLA2G1B P04054 1/20 0.32
▸ ATG4B Q9Y4P1 1/20 0.32
▸ REN P00797 1/20 0.31
▸ GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6126706 1.00 ATM (0.52) ATMCTSKPEPDCTSSACE
SCHEMBL26118721 1.00 ATM (0.52) ATMCTSKPEPDCTSSACE
SCHEMBL26980896 1.00 ATM (0.52) ATMCTSKPEPDCTSSACE
SCHEMBL26980895 1.00 ATM (0.52) ATMCTSKPEPDCTSSACE
SCHEMBL10283713 0.85 ATM (0.71) ATMCTSKPEPDCTSS
SCHEMBL16748604 0.85 ATM (0.71) ATMCTSKPEPDCTSS
SCHEMBL19075564 0.80 ATM (0.46) ATMCTSKPEPDCTSS
SCHEMBL1914224 0.80 ATM (0.34) ATMCTSKPEPDCTSSPLA2G1B
SCHEMBL20474010 0.80 ATM (0.46) ATMCTSKPEPDACEREN
SCHEMBL1914171 0.80 ATM (0.34) ATMCTSKPEPDCTSSPLA2G1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11865108-B2 Nitrogen containing bicyclic compounds WOCKHARDT LIMITED (IN) 2024-01-09 — — US disclosed
EP-4045040-B1 NITROGEN CONTAINING BICYCLIC COMPOUNDS WOCKHARDT LTD (IN) 2023-04-05 — — EP disclosed
CN-114786671-A Nitrogen-containing bicyclic compound 沃克哈特有限公司 2022-07-22 — — CN disclosed
US-11339130-B1 Calpain modulators and therapeutic uses thereof BLADE THERAPEUTICS, INC. (US) 2022-05-24 — — US disclosed
US-10934261-B2 Calpain modulators and therapeutic uses thereof BLADE THERAPEUTICS, INC. (US) 2021-03-02 — — US disclosed
US-10894776-B2 — — 2021-01-19 — — US disclosed
US-20200123114-A1 CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF BLADE THERAPEUTICS, INC. (US) 2020-04-23 — — US disclosed
US-7405201-B2 Antibacterial macrocycles BAYER HEALTHCARE AG (DE) 2008-07-29 — — US disclosed
US-20050107288-A1 Antibacterial macrocycles BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2005-05-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200123114-A1 CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF CAPNS1, CAPN9, CAPN1 ATM 2171/4885CTSK 174/4885PEPD 1889/4885
US-10934261-B2 Calpain modulators and therapeutic uses thereof CAPNS1, CAPN9, CAPN1 ATM 2171/4885CTSK 174/4885PEPD 1889/4885
US-10894776-B2 — CAPNS1, CAPN9, CAPN2 ATM 1783/4885CTSK 307/4885PEPD 2211/4885
US-11339130-B1 Calpain modulators and therapeutic uses thereof CAPNS1, CAPN9, CAPN1 ATM 2171/4885CTSK 174/4885PEPD 1889/4885
US-20050107288-A1 Antibacterial macrocycles MRPL21, RPS17, CFTR ATM 3449/4885CTSK 420/4885PEPD 253/4885
US-11865108-B2 Nitrogen containing bicyclic compounds NUCB2, NRDC, NCF1 ATM 3280/4885CTSK 2502/4885PEPD 555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.