SCHEMBL26569882

SCHEMBL26569882

Cn1ccc2c1ccc1ccn(C)c12

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.44
DHFR P00374 1/20 0.42
CYP2A6 P11509 2/20 0.40
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
NQO2 P16083 1/20 0.38
PIK3CB P42338 1/20 0.36
RHEB Q15382 1/20 0.36
HSD11B1 P28845 3/20 0.33
CCNE2 O96020 1/20 0.33
CDK4 P11802 1/20 0.33
CCND1 P24385 1/20 0.33
CCNE1 P24864 1/20 0.33
CDK2 P24941 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20101422 0.81 PRKCI (0.37) PRKCIDHFRCYP2A6KDM4EALDH1A1
SCHEMBL12278805 0.79 CDK4 (0.38) PRKCICYP2A6PIK3CBCCNE2CDK4
SCHEMBL14985335 0.76 PRKCI (0.45) PRKCIDHFRCYP2A6KDM4EALDH1A1
SCHEMBL822556 0.74 HTR2A (0.50) CYP2A6KDM4EALDH1A1MAPTRXFP1
SCHEMBL12278359 0.74 KDM4E (0.46) PRKCIDHFRCYP2A6KDM4EALDH1A1
SCHEMBL17426202 0.74 KDM4E (0.46) PRKCIDHFRCYP2A6KDM4EALDH1A1
SCHEMBL822778 0.72 ALDH1A1 (0.52) PRKCIDHFRCYP2A6KDM4EALDH1A1
SCHEMBL14985338 0.67 ALDH1A1 (0.42) PRKCIDHFRCYP2A6KDM4EALDH1A1
SCHEMBL14985339 0.67 ALDH1A1 (0.57) PRKCIDHFRCYP2A6KDM4EALDH1A1
SCHEMBL14502422 0.67 KDM4E (0.41) PRKCIDHFRCYP2A6KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337525-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337525-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OXER1 PRKCI 3910/4885DHFR 3025/4885CYP2A6 1536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.