Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4456260 | 0.84 | — | — | |
| SCHEMBL11796395 | 0.79 | — | — | |
| SCHEMBL7516996 | 0.75 | TP53 (0.50) | TP53TSHRTDP1 | |
| SCHEMBL11063662 | 0.75 | TP53 (0.46) | TP53TSHRTDP1 | |
| SCHEMBL14473742 | 0.75 | TP53 (0.33) | TP53TSHRTDP1 | |
| SCHEMBL4456257 | 0.71 | — | — | |
| SCHEMBL4412484 | 0.71 | TP53 (0.31) | TP53TSHRTDP1 | |
| SCHEMBL7528143 | 0.69 | TP53 (0.44) | TP53TSHRTDP1 | |
| SCHEMBL7525524 | 0.69 | TP53 (0.44) | TP53TSHRTDP1 | |
| SCHEMBL1773037 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110301155-A1 | INDAZOLE COMPOUNDS FOR ACTIVATING GLUCOKINASE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-12-08 | — | — | US | disclosed |
| EP-2157859-A1 | INDAZOLE COMPOUNDS FOR ACTIVATING GLUCOKINASE | Takeda Pharmaceutical Company Limited (JP) | 2010-03-03 | — | — | EP | disclosed |
| WO-2008156757-A1 | INDAZOLE COMPOUNDS FOR ACTIVATING GLUCOKINASE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-12-24 | — | — | WO | disclosed |
| EP-0020896-B1 | A METHOD OF FABRICATING DITHIAFULVEN GEMINAL DITHIOLATE COMPOUNDS AND THEIR SELENIUM ANALOGS | International Business Machines Corporation (US) | 1983-11-16 | — | — | EP | disclosed |
| US-4405515-A | Heterofulvalene geminal dithiolate compounds and their selenium and tellurium analogs and a method of fabricating the same | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1983-09-20 | — | — | US | disclosed |
| US-4362662-A | Heterofulvalene geminal dithiolate compounds and their selenium and tellurium analogs and a method of fabricating the same | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1982-12-07 | — | — | US | disclosed |
| US-4312991-A | Dithiobenzoate 4,5-dicyano-1,3-(dithiolidene-2-yl)methylene | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1982-01-26 | — | — | US | disclosed |
| EP-0020896-A1 | A method of fabricating dithiafulven geminal dithiolate compounds and their selenium analogs | International Business Machines Corporation (US) | 1981-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301155-A1 | INDAZOLE COMPOUNDS FOR ACTIVATING GLUCOKINASE | GCKR, GCK, KHK | TP53 4135/4885TSHR 1056/4885TDP1 4552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.