Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 2/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.59 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.59 |
| ▸ | USP5 | P45974 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26572451 | 0.90 | PTPRC (0.51) | PTPRCCTSLPTPN13USP5KDM4E | |
| SCHEMBL26116582 | 0.84 | MAPK14 (0.52) | PTPRCCTSLPTPN13KDM4EALDH1A1 | |
| SCHEMBL26570867 | 0.83 | PTPRC (0.63) | PTPRCCTSLPTPN13ALDH1A1HPGD | |
| SCHEMBL438531 | 0.82 | PTPRC (0.59) | PTPRCCTSLPTPN13USP5KDM4E | |
| SCHEMBL26113792 | 0.82 | MCHR1 (0.48) | PTPRCCTSLPTPN13KDM4EALDH1A1 | |
| SCHEMBL342843 | 0.81 | KDM4E (0.56) | PTPRCCTSLPTPN13USP5KDM4E | |
| SCHEMBL6989058 | 0.80 | CTDSP1 (0.61) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL30147610 | 0.80 | PTGS1 (0.51) | ALDH1A1HPGDSMN1; SMN2MAPTHIF1A | |
| SCHEMBL26118039 | 0.80 | PTPRC (0.88) | PTPRCCTSLPTPN13USP5KDM4E | |
| SCHEMBL29195031 | 0.78 | KDM4E (0.53) | PTPRCCTSLPTPN13USP5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |