Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 4/20 | 0.63 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31725067 | 0.86 | PTPRC (0.65) | PTPRCGABRA5ALDH1A1CTSLPTPN13 | |
| SCHEMBL26570869 | 0.83 | PTPRC (0.59) | PTPRCSMN1; SMN2ALDH1A1LMNACYP2C19 | |
| SCHEMBL30759189 | 0.79 | PTPRC (0.55) | PTPRCSMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL27113111 | 0.79 | PTPRC (0.55) | PTPRCSMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL6084716 | 0.78 | PTPRC (0.62) | PTPRCSMN1; SMN2LMNARAB9A | |
| SCHEMBL6260964 | 0.78 | PTPRC (1.00) | PTPRCSMN1; SMN2ALDH1A1LMNACTSL | |
| SCHEMBL6261925 | 0.78 | PTPRC (1.00) | PTPRCALDH1A1CTSLPTPN13MAPT | |
| SCHEMBL20458935 | 0.77 | MTNR1A (0.51) | LMNACYP2C19MAPTMTNR1AMTNR1B | |
| SCHEMBL26572450 | 0.77 | KMT2A (0.56) | SMN1; SMN2ALDH1A1LMNACYP2C19CYP3A4 | |
| SCHEMBL26567156 | 0.77 | PTPRC (0.46) | PTPRCSMN1; SMN2LMNACYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |