Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | FASN | P49327 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31067069 | 0.87 | GRM2 (0.48) | HSD11B1GRM2GCGRMAPK14PTGS2 | |
| SCHEMBL1262207 | 0.87 | GRM2 (0.48) | HSD11B1GRM2GCGRMAPK14PTGS2 | |
| SCHEMBL31066929 | 0.85 | GRM2 (0.47) | HSD11B1GRM2GCGRMAPK14PTGS2 | |
| SCHEMBL12999476 | 0.84 | ABL1 (0.47) | HSD11B1ACHEGCGRMAPK14MEN1 | |
| SCHEMBL19323001 | 0.83 | HPGD (0.45) | ACHEMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL24196502 | 0.80 | GRM2 (0.43) | HSD11B1GRM2GCGRMAPK14PTGS2 | |
| SCHEMBL22452543 | 0.80 | TAAR1 (0.47) | HSD11B1GRM2GCGRMAPK14PTGS2 | |
| SCHEMBL11693196 | 0.80 | ESR1 (0.52) | GRM2MEN1KMT2AFASNSMN1; SMN2 | |
| SCHEMBL11694239 | 0.79 | GSK3B (0.48) | GCGRMAPK14MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15060599 | 0.79 | GRM2 (0.50) | HSD11B1GRM2GCGRMAPK14MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |