Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 2/20 | 0.47 |
| ▸ | GCGR | P47871 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31265226 | 1.00 | GSK3B (0.48) | GSK3BSYKGCGRMAPK14ALDH1A1 | |
| SCHEMBL1262207 | 0.82 | GRM2 (0.48) | GCGRMAPK14KDM4ENPC1RAB9A | |
| SCHEMBL31067069 | 0.82 | GRM2 (0.48) | GCGRMAPK14KDM4ENPC1RAB9A | |
| SCHEMBL6068558 | 0.81 | CYP2C19 (0.55) | GSK3BSYKGCGRMAPK14ALDH1A1 | |
| SCHEMBL31066929 | 0.81 | GRM2 (0.47) | GCGRMAPK14KDM4ENPC1RAB9A | |
| SCHEMBL11691477 | 0.80 | SYK (0.48) | GSK3BSYKGCGRMAPK14ALDH1A1 | |
| SCHEMBL26572467 | 0.79 | HSD11B1 (0.46) | GCGRMAPK14KDM4EMEN1KMT2A | |
| SCHEMBL16297083 | 0.78 | CYP1A1 (0.51) | MAPK14ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL30979851 | 0.78 | NFE2L2 (0.51) | GSK3BSYKGCGRMAPK14ALDH1A1 | |
| SCHEMBL1848218 | 0.78 | OPRD1 (0.55) | GSK3BMAPK14KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4044049-A | Phenyl benzoic acid compounds | MERCK & CO., INC. (US) | 1977-08-23 | — | — | US | disclosed |