Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30571904 | 1.00 | KDM4E (0.44) | KDM4EMEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL26116013 | 0.88 | PTPRC (0.51) | KDM4ESMN1; SMN2ALDH1A1PDK2PTPRC | |
| SCHEMBL26573347 | 0.87 | KDM4E (0.50) | KDM4EMEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL26560867 | 0.87 | PDK2 (0.58) | KDM4EMEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL26117162 | 0.84 | PDK2 (0.55) | KDM4EMEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL26115897 | 0.81 | PDK2 (0.53) | KDM4ESMN1; SMN2HSD17B10ALDH1A1PDK2 | |
| SCHEMBL26572934 | 0.81 | ALDH1A1 (0.46) | KDM4EMEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL30571474 | 0.80 | MAPK1 (0.44) | KDM4EMEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL26120236 | 0.77 | PDK2 (0.48) | KDM4ETSHRSMN1; SMN2ALDH1A1PDK2 | |
| SCHEMBL26573487 | 0.76 | PDK2 (0.43) | KMT2AALDH1A1PDK2PTPRCMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |