Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | LIPA | P38571 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28858882 | 0.98 | EPHX1 (0.36) | EPHX1GLALIPAALDH1A1ATM | |
| SCHEMBL1837143 | 0.80 | FFAR3 (0.54) | EPHX1GLALIPAALDH1A1ATM | |
| SCHEMBL13446511 | 0.78 | EPHX1 (0.35) | EPHX1GLALIPAALDH1A1ATM | |
| SCHEMBL29282866 | 0.78 | EPHX1 (0.35) | EPHX1GLALIPAALDH1A1ATM | |
| SCHEMBL4601909 | 0.78 | GRM4 (0.47) | EPHX1GLAALDH1A1CYP2D6GAA | |
| SCHEMBL4601083 | 0.78 | GRM4 (0.47) | EPHX1GLAALDH1A1CYP2D6GAA | |
| SCHEMBL17041434 | 0.75 | LIPA (0.35) | EPHX1GLALIPAALDH1A1ATM | |
| SCHEMBL13464471 | 0.75 | HSD11B1 (0.36) | EPHX1GLALIPAALDH1A1ATM | |
| SCHEMBL3420703 | 0.73 | CYP2C19 (0.38) | EPHX1ALDH1A1FFAR3LMNACYP2C19 | |
| SCHEMBL9261087 | 0.72 | CYP1A2 (0.46) | EPHX1GLALIPAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118085403-A | Mg-P composite modified flame retardant, flame-retardant PMI foam and preparation method and application thereof | 湖南博翔新材料有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-114874483-B | PMI foam material and preparation method and application thereof | 湖南博翔新材料有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-116462791-A | Multifunctional polymethacrylimide foam material and preparation method and application thereof | 湖南博翔新材料有限公司 | 2023-07-21 | — | — | CN | claimed |
| EP-4116367-B1 | CRYSTAL NUCLEATING AGENT COMPOSITION FOR POLYOLEFIN RESIN, AND POLYOLEFIN RESIN COMPOSITION INCLUDING SAID CRYSTAL NUCLEATING AGENT COMPOSITION | NEW JAPAN CHEM CO LTD (JP) | 2024-12-04 | — | — | EP | disclosed |
| CN-115210313-B | Crystallization nucleating agent composition for polyolefin resin and polyolefin resin composition comprising the same | 新日本理化株式会社 | 2024-05-24 | — | — | CN | disclosed |
| CN-114874483-B | PMI foam material and preparation method and application thereof | 湖南博翔新材料有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-116462791-A | Multifunctional polymethacrylimide foam material and preparation method and application thereof | 湖南博翔新材料有限公司 | 2023-07-21 | — | — | CN | disclosed |
| US-20230183451-A1 | CRYSTAL NUCLEATING AGENT COMPOSITION FOR POLYOLEFIN RESIN, AND POLYOLEFIN RESIN COMPOSITION INCLUDING SAID CRYSTAL NUCLEATING AGENT COMPOSITION | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2023-06-15 | — | — | US | disclosed |
| EP-4116367-A1 | CRYSTAL NUCLEATING AGENT COMPOSITION FOR POLYOLEFIN RESIN, AND POLYOLEFIN RESIN COMPOSITION INCLUDING SAID CRYSTAL NUCLEATING AGENT COMPOSITION | New Japan Chemical Co., Ltd. (JP) | 2023-01-11 | — | — | EP | disclosed |
| CN-115210313-A | Crystal nucleating agent composition for polyolefin resin and polyolefin resin composition containing the same | 新日本理化株式会社 | 2022-10-18 | — | — | CN | disclosed |
| CN-101029080-A | Methods and compositions for derepression of IAP-inhibited caspase | BURNHAM INST (US) | 2007-09-05 | — | — | CN | disclosed |
| EP-1569915-A4 | SPIROCYCLIC UREAS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO INC (US) | 2007-07-11 | — | — | EP | disclosed |
| US-20060116366-A1 | Spirocyclic ureas, compositions containing such compounds and methods of use | MERCK & CO., INC. | 2006-06-01 | — | — | US | disclosed |
| EP-1569915-A2 | SPIROCYCLIC UREAS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | Merck & Co., Inc. (US) | 2005-09-07 | — | — | EP | disclosed |
| CN-1615148-A | Methods and compositions for derepression of IAP-inhibited caspase | BURNHAM INST (US) | 2005-05-11 | — | — | CN | disclosed |
| WO-2004050039-A2 | SPIROCYCLIC UREAS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE | MERCK & CO., INC. (US) | 2004-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116366-A1 | Spirocyclic ureas, compositions containing such compounds and methods of use | UTS2R, GLP1R, GCGR | EPHX1 3048/4885GLA 651/4885LIPA 1299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.