SCHEMBL26575337

SCHEMBL26575337

Cc1cc(/C=C/C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc(C)c1NC(=O)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.35
CA2 P00918 6/20 0.35
GAA P10253 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
ITGB3 P05106 1/20 0.32
ITGB1 P05556 1/20 0.32
ITGAV P06756 1/20 0.32
ITGA2B P08514 1/20 0.32
ITGB5 P18084 1/20 0.32
HTT P42858 2/20 0.31
PRKCA P17252 1/20 0.31
PDK1 Q15118 1/20 0.31
PDK2 Q15119 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26111141 1.00 CA1 (0.35) CA1CA2GAACYP1A2CYP2C9
SCHEMBL27429907 0.88 CA1 (0.37) CA1CA2GAACYP1A2CYP2C9
SCHEMBL26114266 0.74 POLB (0.33)
SCHEMBL26575440 0.74 POLB (0.33)
SCHEMBL12311030 0.74 CYP1A2 (0.37) CA1CA2CYP1A2CYP2C9CYP2C19
SCHEMBL12311032 0.73 AKR1C3 (0.37) CYP1A2CYP2C9L3MBTL1ITGB3ITGB1
SCHEMBL26575340 0.72 HDAC1 (0.36) CA1CA2GAACYP1A2CYP2C9
SCHEMBL26575330 0.71 ALDH1A1 (0.55) L3MBTL1HTT
SCHEMBL26112011 0.71
SCHEMBL26575450 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023196594-A2 SABRE CATALYSTS CONTAINING FLUORINATED CARBON CHAINS FOR DELIVERY OF METAL-FREE MRI CONTRAST AGENTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-10-12 WO disclosed
WO-2023196602-A1 INFUSION DEVICE FOR THE PREPARATION AND DELIVERY OF MRI PROBES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-10-12 WO disclosed