Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | RXFP2 | Q8WXD0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.38 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL273692 | 1.00 | AURKA (0.41) | AURKARPS6KB1KMT2AMEN1OPRK1 | |
| SCHEMBL273628 | 0.86 | NPSR1 (0.52) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL268798 | 0.86 | NPSR1 (0.52) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL273687 | 0.86 | GRM4 (0.53) | KMT2AMEN1OPRK1POLBLMNA | |
| SCHEMBL267372 | 0.86 | NPC1 (0.48) | KMT2AMEN1RXFP1POLBLMNA | |
| SCHEMBL266825 | 0.86 | GRM4 (0.53) | KMT2AMEN1OPRK1POLBLMNA | |
| SCHEMBL273927 | 0.86 | NPC1 (0.48) | KMT2AMEN1RXFP1POLBLMNA | |
| SCHEMBL267373 | 0.86 | NPC1 (0.48) | KMT2AMEN1RXFP1POLBLMNA | |
| SCHEMBL267208 | 0.83 | KMT2A (0.50) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL273362 | 0.83 | KMT2A (0.50) | KMT2AMEN1POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134015-B2 | Compound inhibiting in vivo phosphorous transport and medicine containing the same | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-03-13 | — | — | US | disclosed |