Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 8/20 | 0.52 |
| ▸ | PKM | P14618 | 4/20 | 0.52 |
| ▸ | TUBB8B | A6NNZ2 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL273628 | 1.00 | NPSR1 (0.52) | NPSR1MEN1KMT2AHTTNPC1 | |
| SCHEMBL265755 | 0.86 | AURKA (0.41) | NPSR1MEN1KMT2AHTTNPC1 | |
| SCHEMBL273692 | 0.86 | AURKA (0.41) | NPSR1MEN1KMT2AHTTNPC1 | |
| SCHEMBL266825 | 0.84 | GRM4 (0.53) | NPSR1MEN1KMT2ANPC1PKM | |
| SCHEMBL273687 | 0.84 | GRM4 (0.53) | NPSR1MEN1KMT2ANPC1PKM | |
| SCHEMBL266792 | 0.84 | KMT2A (0.62) | NPSR1MEN1KMT2ANPC1PKM | |
| SCHEMBL273626 | 0.84 | KMT2A (0.62) | NPSR1MEN1KMT2ANPC1PKM | |
| SCHEMBL266460 | 0.83 | POLB (0.46) | NPSR1MEN1KMT2ANPC1PKM | |
| SCHEMBL273472 | 0.83 | POLB (0.46) | NPSR1MEN1KMT2ANPC1PKM | |
| SCHEMBL267373 | 0.82 | NPC1 (0.48) | NPSR1MEN1KMT2ANPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134015-B2 | Compound inhibiting in vivo phosphorous transport and medicine containing the same | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-03-13 | — | — | US | disclosed |