Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2072152 | 1.00 | GCK (0.58) | GCKKCNH2 | |
| SCHEMBL2072154 | 0.90 | GCK (0.62) | GCKKCNH2 | |
| SCHEMBL2073632 | 0.83 | GCK (0.56) | GCKKCNH2 | |
| SCHEMBL2669717 | 0.81 | GCK (0.41) | GCKKCNH2 | |
| SCHEMBL2657879 | 0.81 | GCK (0.65) | GCKKCNH2 | |
| SCHEMBL2074921 | 0.81 | GCK (0.65) | GCKKCNH2 | |
| SCHEMBL2657926 | 0.77 | GCK (0.49) | GCKKCNH2 | |
| SCHEMBL2072002 | 0.77 | GCK (0.49) | GCKKCNH2 | |
| SCHEMBL2074591 | 0.77 | GCK (0.48) | GCKKCNH2 | |
| SCHEMBL2653806 | 0.76 | GCK (0.87) | GCKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086964-A2 | BENZOYL AMINO HETEROCYCLYL COMPOUNDS USEFUL IN THE TREATMENT OF A DISEASE MEDIATED THROUGH GLK | Astra Zeneca AB (SE) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008050101-A2 | BENZOYL AMINO HETEROCYCLYL COMPOUNDS USEFUL IN THE TREATMENT OF A DISEASE MEDIATED THROUGH GLK | ASTRAZENECA AB (SE) | 2008-05-02 | — | — | WO | disclosed |