Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26846380 | 0.88 | SCN4A (0.34) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL26575699 | 0.85 | MEN1 (0.30) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL26575341 | 0.85 | NPC1 (0.32) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL24298810 | 0.85 | AAK1 (0.34) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL22509294 | 0.85 | AAK1 (0.34) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL24324604 | 0.84 | NR1H4 (0.32) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL24323678 | 0.84 | NR1H4 (0.33) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL24324167 | 0.84 | — | — | |
| SCHEMBL24324613 | 0.84 | — | — | |
| SCHEMBL30588763 | 0.84 | CASP3 (0.38) | MEN1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023196429-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-10-12 | — | — | WO | disclosed |