SCHEMBL26587

SCHEMBL26587

CN(C)OCCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17607 0.83 TSHR (0.39)
SCHEMBL1251073 0.82 MEN1 (0.61)
Fluoride SCHEMBL1811141 0.80 TSHR (0.37)
Trimethylammonium SCHEMBL5918857 0.80 TSHR (0.37)
Fluoride SCHEMBL28910326 0.80 TSHR (0.37)
Ammonia Solution, Strong SCHEMBL1170676 0.80 TSHR (0.37)
Bromide SCHEMBL8460965 0.80 TSHR (0.37)
SCHEMBL17703415 0.80
Hydrochloric Acid SCHEMBL8075611 0.80 TSHR (0.37)
Ethylene Glycol SCHEMBL28558188 0.80 TSHR (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7634 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11970711-B2 Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-04-30 US claimed
CN-117083385-A Targeting oncogenic mutations with double-cleaving endonucleases 特定生物制品公司 2023-11-17 CN claimed
CN-117003652-A N, N-dimethylamino glycol ether, preparation thereof and application thereof as regulator of polymeric structure 中国石油化工股份有限公司 2023-11-07 CN claimed
US-11795472-B2 RNA-guided nucleic acid modifying enzymes and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-24 US claimed
WO-2023201203-A2 CRISPR-CAS EFFECTOR POLYPEPTIDES AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-19 WO claimed
EP-4240839-A1 GENE EDITING WITH A MODIFIED ENDONUCLEASE Specific Biologics Inc. (CA) 2023-09-13 EP claimed
CN-116669775-A Gene editing with modified endonucleases 特定生物制品公司 2023-08-29 CN claimed
WO-2023107531-A2 ANTISENSE OLIGONUCLEOTIDE DRUG TARGETS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-06-15 WO claimed
US-11674159-B2 Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-06-13 US claimed
US-20230174979-A1 METHODS AND COMPOSITIONS FOR TREATING ATAXIA TELANGIECTASIA CHILDREN’S MEDICAL CENTER CORPORATION (US) 2023-06-08 US claimed
EP-1119579-A4 ANTISENSE MODULATION OF BCL-X EXPRESSION ISIS PHARMACEUTICALS INC (US) 2003-01-29 EP claimed
EP-1263765-A1 ALTERATION OF CELLULAR BEHAVIOR BY ANTISENSE MODULATION OF mRNA PROCESSING ISIS PHARMACEUTICALS, INC. (US) 2002-12-11 EP claimed
JP-2002526093-A 2002-08-20 JP claimed
WO-2001072765-A1 ALTERATION OF CELLULAR BEHAVIOR BY ANTISENSE MODULATION OF mRNA PROCESSING ISIS PHARMACEUTICALS, INC. (US) 2001-10-04 WO claimed
EP-1119579-A1 ANTISENSE MODULATION OF BCL-X EXPRESSION ISIS PHARMACEUTICALS, INC. (US) 2001-08-01 EP claimed
US-20010007025-A1 Antisense modulation of bcl-x expression ISIS PHARMACEUTICALS, INC. 2001-07-05 US claimed
US-6214986-B1 OLIGONUCLEOTIDE OF DEFINED NUCLEOTIDE SEQUENCE TARGETED TO HUMAN PROTEIN WHICH CONTROLS APOPTOSIS; ALTERS RATIOS OF ISOFORMS IN TISSUE; GENE EXPRESSION INHIBITION; SENSITIZING CELLS TO APOPTOTIC STIMULI ISIS PHARMACEUTICALS, INC. 2001-04-10 US claimed
US-6210892-B1 HYBRIDIZING AN ANTISENSE COMPOUND HAVING A 2' SUGAR, MORPHOLINO, OR PEPTIDE NUCLEIC ACID MODIFICATION TO TARGET MESSENGER RNA TO CHANGE ITS PROCESSING INCLUDING SPLICING, POLYADENYLATION OR STABILITY ISIS PHARMACEUTICALS, INC. 2001-04-03 US claimed
WO-2000020432-A1 ANTISENSE MODULATION OF BCL-X EXPRESSION ISIS PHARMACEUTICALS, INC. (US) 2000-04-13 WO claimed
WO-2000004189-A1 MODIFIED OLIGONUCLEOTIDES ISIS PHARMACEUTICALS, INC. (US) 2000-01-27 WO claimed