Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17607 | 0.97 | TSHR (0.39) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| Methyl Alcohol SCHEMBL28027678 | 0.94 | TSHR (0.37) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8075611 | 0.94 | TSHR (0.37) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| Ethylene Glycol SCHEMBL28558188 | 0.94 | TSHR (0.37) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| Water SCHEMBL11295479 | 0.94 | TSHR (0.37) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL1170676 | 0.94 | TSHR (0.37) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| Fluoride SCHEMBL28910326 | 0.94 | TSHR (0.37) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| Fluoride SCHEMBL1811141 | 0.94 | TSHR (0.37) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| Fluoride SCHEMBL28675142 | 0.91 | TSHR (0.35) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| Chloromethane SCHEMBL28006061 | 0.91 | TSHR (0.35) | TSHRMAPK1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858921-A | Glyphosate herbicidal and plant growth regulant compositions and their use | ALBEMARLE CORPORATION (US) | 1999-01-12 | — | — | US | disclosed |
| WO-1997036494-A1 | HERBICIDAL AND PLANT GROWTH REGULANT COMPOSITIONS AND THEIR USE | ALBEMARLE CORPORATION (US) | 1997-10-09 | — | — | WO | disclosed |