Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 18/20 | 0.47 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | BLK | P51451 | 2/20 | 0.41 |
| ▸ | TEC | P42680 | 2/20 | 0.41 |
| ▸ | BMX | P51813 | 2/20 | 0.41 |
| ▸ | ITK | Q08881 | 2/20 | 0.41 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | TXK | P42681 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | CD69 | Q07108 | 1/20 | 0.40 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.40 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30582498 | 0.97 | BTK (0.50) | BTKEGFRBLKTECBMX | |
| SCHEMBL26587174 | 0.93 | BTK (0.47) | BTKEGFRBLKTECBMX | |
| SCHEMBL26587446 | 0.90 | FGFR2 (0.50) | BTKITKFGFR2FGFR1FGFR4 | |
| SCHEMBL26108691 | 0.88 | SRC (0.41) | BTKEGFRRET | |
| SCHEMBL30582586 | 0.88 | SRC (0.41) | BTKEGFRRET | |
| SCHEMBL26587732 | 0.88 | BTK (0.44) | BTKEGFRITKFGFR2FGFR1 | |
| SCHEMBL26587704 | 0.88 | FGFR4 (0.44) | BTKEGFRITKFGFR2FGFR1 | |
| SCHEMBL22673393 | 0.87 | BTK (0.49) | BTKEGFRBLKTECBMX | |
| SCHEMBL26587541 | 0.87 | FGFR1 (0.47) | BTKEGFRBLKFGFR2FGFR1 | |
| SCHEMBL26588196 | 0.86 | NUDT14 (0.39) | BTKFGFR2FGFR1FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499616-A1 | SPIROBICYCLIC COMPOUNDS | Acerand Therapeutics (Hong Kong) Limited (HK) | 2025-02-05 | — | — | EP | claimed |
| CN-119013260-A | Spirobicyclic compounds | 优领医药科技(香港)有限公司 | 2024-11-22 | — | — | CN | claimed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | claimed |
| EP-4499616-A1 | SPIROBICYCLIC COMPOUNDS | Acerand Therapeutics (Hong Kong) Limited (HK) | 2025-02-05 | — | — | EP | disclosed |
| CN-119013260-A | Spirobicyclic compounds | 优领医药科技(香港)有限公司 | 2024-11-22 | — | — | CN | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |