Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2659027 | 1.00 | GCK (0.47) | GCKOPRM1OPRL1CDK5CDK5R1 | |
| SCHEMBL2662383 | 0.80 | GCK (0.56) | GCK | |
| SCHEMBL3388057 | 0.80 | GCK (0.56) | GCK | |
| SCHEMBL3389184 | 0.77 | GCK (0.54) | GCK | |
| SCHEMBL3389187 | 0.77 | GCK (0.54) | GCK | |
| SCHEMBL2652348 | 0.68 | GCK (0.52) | GCK | |
| SCHEMBL2652345 | 0.68 | GCK (0.52) | GCK | |
| SCHEMBL2665295 | 0.67 | GCK (0.57) | GCK | |
| SCHEMBL3389196 | 0.66 | GCK (0.53) | GCKLMNASMN1; SMN2 | |
| SCHEMBL2662459 | 0.66 | GCK (0.53) | GCKLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594867-A2 | PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS | Prosidion Limited (GB) | 2005-11-16 | — | — | EP | claimed |
| WO-2004072031-A2 | PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS | PROSIDION LIMITED (GB) | 2004-08-26 | — | — | WO | claimed |