Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2660409 | 0.93 | ALDH1A1 (0.38) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL2659469 | 0.93 | ALDH1A1 (0.37) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL2661414 | 0.92 | ALDH1A1 (0.37) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| Trifluoroacetic Acid SCHEMBL2972238 | 0.92 | ALDH1A1 (0.45) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL13203395 | 0.91 | ALDH1A1 (0.49) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL2973942 | 0.90 | BCHE (0.32) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| Trifluoroacetic Acid SCHEMBL2660377 | 0.89 | MAPT (0.43) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL9072964 | 0.88 | MAPT (0.45) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| Trifluoroacetic Acid SCHEMBL2973940 | 0.88 | CNR2 (0.35) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL2968235 | 0.88 | GCK (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074119-A1 | INDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |