Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 14/20 | 0.65 |
| ▸ | CNR2 | P34972 | 14/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CFD | P00746 | 1/20 | 0.46 |
| ▸ | ICMT | O60725 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980705 | 0.84 | KDM4E (0.57) | CNR1CNR2HDAC1HDAC2HDAC6 | |
| SCHEMBL12479681 | 0.82 | CNR1 (0.47) | CNR1CNR2HDAC1HDAC2HDAC6 | |
| SCHEMBL2076365 | 0.79 | CNR2 (1.00) | CNR1CNR2 | |
| SCHEMBL1607278 | 0.78 | CNR1 (0.52) | CNR1CNR2 | |
| SCHEMBL12480004 | 0.77 | SYK (0.44) | CNR1CNR2HDAC1HDAC2HDAC6 | |
| SCHEMBL7291403 | 0.77 | CNR1 (0.60) | CNR1CNR2 | |
| SCHEMBL5646976 | 0.77 | CNR1 (0.90) | CNR1CNR2 | |
| SCHEMBL3581287 | 0.75 | CNR1 (0.66) | CNR1CNR2ICMT | |
| SCHEMBL12480795 | 0.74 | ALDH1A1 (0.55) | CNR1CNR2CFD | |
| SCHEMBL1993865 | 0.74 | CNR1 (0.52) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532980-A1 | N-heteroaryl indole carboxamides and analogues thereof, for use as glucokinase activators in the treatment of diabetes | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |