Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADH1B | P00325 | 2/20 | 0.33 |
| ▸ | ADH1C | P00326 | 2/20 | 0.33 |
| ▸ | ADH1A | P07327 | 2/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | ADH7 | P40394 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2648425 | 1.00 | ALDH1A1 (0.52) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL2648633 | 1.00 | ALDH1A1 (0.52) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL2648934 | 0.82 | ALDH1A1 (0.57) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL2648250 | 0.82 | ALDH1A1 (0.57) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL2648937 | 0.82 | ALDH1A1 (0.57) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL2648254 | 0.82 | ALDH1A1 (0.57) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL20887775 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL2649070 | 0.79 | ALDH1A1 (0.52) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL2648902 | 0.79 | ALDH1A1 (0.52) | ALDH1A1HSD17B10THRBATML3MBTL1 | |
| SCHEMBL2648810 | 0.79 | ALDH1A1 (0.48) | ALDH1A1HSD17B10THRBATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904466-A1 | DICYCLOALKYL UREA GLUCOKINASE ACTIVATORS | Novo Nordisk A/S (DK) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007006760-A1 | DICYCLOALKYL UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |