SCHEMBL26598409

SCHEMBL26598409

O=C(Sc1ccc(C2(C(F)(F)F)N=N2)cc1)c1ccc(C2(C(F)(F)F)N=N2)cc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.47
NOS1 P29475 2/20 0.36
MAPT P10636 5/20 0.35
ALDH1A1 P00352 3/20 0.35
GABRA1 P14867 3/20 0.34
GABRB2 P47870 2/20 0.34
LMNA P02545 3/20 0.34
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
NTRK1 P04629 1/20 0.32
SLC2A1 P11166 1/20 0.31
ALPG P10696 1/20 0.31
TERT O14746 1/20 0.31
SIRT2 Q8IXJ6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26598420 0.93 KIF11 (0.42) KIF11NOS1MAPTALDH1A1GABRA1
SCHEMBL2380170 0.79 KIF11 (0.51) KIF11NOS1ALDH1A1
SCHEMBL13073461 0.77 KIF11 (0.50) KIF11NOS1MAPTGABRA1GABRB2
SCHEMBL20809262 0.77 KIF11 (0.50) KIF11NOS1ALDH1A1GABRA1GABRB2
SCHEMBL2438979 0.77 KIF11 (0.58) KIF11NOS1MAPTALDH1A1GABRA1
SCHEMBL26623845 0.76 KIF11 (0.44) KIF11ALDH1A1GABRA1GABRB2GABRG2
SCHEMBL26624004 0.76 KIF11 (0.44) KIF11NOS1GABRA1GABRB2GABRG2
SCHEMBL26598413 0.76 KIF11 (0.49) KIF11NOS1GABRA1GABRB2LMNA
SCHEMBL19733924 0.75 KIF11 (0.48) KIF11NOS1GABRA1GABRB2GABRG2
SCHEMBL14655025 0.75 KIF11 (0.51) KIF11HTTNTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250270385-A1 DYNAMICALLY CROSSLINKED MULTIBLOCK COPOLYMERS FOR COMPATIBILIZING IMMISCIBLE MIXED PLASTICS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2025-08-28 US disclosed
WO-2023205071-A2 DYNAMICALLY CROSSLINKED MULTIBLOCK COPOLYMERS FOR COMPATIBILIZING IMMISCIBLE MIXED PLASTICS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2023-10-26 WO disclosed
WO-2023205071-A2 DYNAMICALLY CROSSLINKED MULTIBLOCK COPOLYMERS FOR COMPATIBILIZING IMMISCIBLE MIXED PLASTICS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2023-10-26 WO disclosed