Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 7/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | CDK4 | P11802 | 2/20 | 0.38 |
| ▸ | CCND1 | P24385 | 2/20 | 0.38 |
| ▸ | CCND3 | P30281 | 2/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1F | P30939 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26599818 | 0.92 | TYK2 (0.47) | TYK2DYRK1AKCNH2CDK4CCND1 | |
| SCHEMBL25437185 | 0.90 | TYK2 (0.40) | TYK2DYRK1AKCNH2JAK1GSK3B | |
| SCHEMBL31185868 | 0.82 | TYK2 (0.47) | TYK2DYRK1AKCNH2CDK4CCND1 | |
| SCHEMBL26599338 | 0.82 | TYK2 (0.47) | TYK2DYRK1AKCNH2CDK4CCND1 | |
| SCHEMBL26599329 | 0.82 | TYK2 (0.47) | TYK2DYRK1AKCNH2CDK4CCND1 | |
| SCHEMBL30511737 | 0.78 | TYK2 (0.46) | TYK2JAK1HTR1AHTR1DHTR1F | |
| SCHEMBL21330032 | 0.78 | TYK2 (0.46) | TYK2JAK1HTR1AHTR1DHTR1F | |
| SCHEMBL26599444 | 0.77 | RORC (0.37) | TYK2JAK1GSK3BPIK3C3HTR1A | |
| SCHEMBL26599197 | 0.74 | MAPK1 (0.44) | TYK2DYRK1ACDK4CCND1CCND3 | |
| SCHEMBL26599203 | 0.74 | MAPK1 (0.44) | TYK2DYRK1ACDK4CCND1CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339977-A1 | SUBSTITUTED HETEROARYL COMPOUND, AND COMPOSITION AND APPLICATION THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2023-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339977-A1 | SUBSTITUTED HETEROARYL COMPOUND, AND COMPOSITION AND APPLICATION THEREOF | TYK2, JAK1, JAK3 | TYK2 1/4885DYRK1A 35/4885KCNH2 3128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.