Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 2/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 11/20 | 0.35 |
| ▸ | SRC | P12931 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2977950 | 0.84 | FGFR1 (0.39) | PRKCIFGFR1SRCMAPK1SMN1; SMN2 | |
| SCHEMBL2974092 | 0.83 | FGFR1 (0.38) | PRKCIFGFR1SRCMAPK1SMN1; SMN2 | |
| SCHEMBL2976805 | 0.83 | PRKCI (0.44) | PRKCIFGFR1SRCMAPK1SMN1; SMN2 | |
| SCHEMBL2966390 | 0.81 | FGFR1 (0.44) | PRKCIFGFR1SRCMAPK1SMN1; SMN2 | |
| SCHEMBL2963434 | 0.81 | SIGMAR1 (0.38) | FGFR1SMN1; SMN2GABRA1GABRG2GABRB3 | |
| SCHEMBL2652696 | 0.80 | FGFR1 (0.36) | PRKCIFGFR1SRCMAPK1SMN1; SMN2 | |
| SCHEMBL2964600 | 0.78 | HPGD (0.45) | FGFR1MAPK1SMN1; SMN2GABRA1GABRG2 | |
| SCHEMBL2968176 | 0.71 | MAOB (0.39) | — | |
| SCHEMBL27984245 | 0.70 | TAAR1 (0.44) | MAPK1SMN1; SMN2 | |
| SCHEMBL28722140 | 0.70 | HPGD (0.54) | FGFR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874758-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | NEUROSEARCH A/S (DK) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006111516-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | NEUROSEARCH A/S (DK) | 2006-10-26 | — | — | WO | disclosed |