Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 9/20 | 0.63 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3917783 | 0.88 | HRH4 (0.61) | HRH4HRH3CYP1A2CYP2C9ADRB1 | |
| SCHEMBL11042359 | 0.87 | HRH3 (0.65) | HRH4HRH3CYP1A2CYP2C9ADRB1 | |
| Trifluoroacetic Acid SCHEMBL5038086 | 0.85 | HRH4 (0.58) | HRH4HRH3CYP1A2CYP2C9ADRB1 | |
| Trifluoroacetic Acid SCHEMBL30618987 | 0.80 | HRH4 (0.62) | HRH4HRH3CYP1A2CYP2C9ADRB1 | |
| Trifluoroacetic Acid SCHEMBL26600738 | 0.80 | HRH4 (0.62) | HRH4HRH3CYP1A2CYP2C9ADRB1 | |
| Trifluoroacetic Acid SCHEMBL26600662 | 0.79 | HRH4 (0.58) | HRH4HRH3CYP1A2CYP2C9ADRB1 | |
| Trifluoroacetic Acid SCHEMBL26600666 | 0.77 | ADRB1 (0.57) | HRH4HRH3ADRB1ADRB2 | |
| SCHEMBL2850464 | 0.77 | HRH3 (0.59) | HRH4HRH3CYP1A2CYP2C9ADRB1 | |
| SCHEMBL26599637 | 0.76 | HRH4 (0.52) | HRH4HRH3CYP1A2CYP2C9ADRB1 | |
| Trifluoroacetic Acid SCHEMBL5038083 | 0.76 | HRH4 (0.52) | HRH4HRH3CYP1A2CYP2C9ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12454547-B2 | Steroidal compositions and methods of treating lipogenic cancers | Asteroid Therapeutics (US) | 2025-10-28 | — | — | US | disclosed |
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | Asteroid Therapeutics | 2023-10-26 | — | — | US | disclosed |
| WO-2023205801-A2 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | Asteroid Therapeutics (US) | 2023-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12454547-B2 | Steroidal compositions and methods of treating lipogenic cancers | SREBF1, SREBF2, NR1H3 | HRH4 4558/4885HRH3 4494/4885CYP1A2 935/4885 |
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | SREBF1, SREBF2, NR1H3 | HRH4 4558/4885HRH3 4494/4885CYP1A2 935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.