Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31322070 | 0.84 | SLC6A3 (0.51) | KDM4EALDH1A1KMT2ASLC6A3SLC6A4 | |
| SCHEMBL31207927 | 0.83 | KDM4C (0.44) | KDM4EALDH1A1KMT2AL3MBTL1CCNC | |
| SCHEMBL26600023 | 0.83 | KDM4C (0.44) | KDM4EALDH1A1KMT2AL3MBTL1CCNC | |
| SCHEMBL19284336 | 0.81 | KDM4E (0.58) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL31584153 | 0.81 | KDM4E (0.58) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL21056662 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL31119793 | 0.79 | SLC22A12 (0.56) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL22717408 | 0.79 | SLC22A12 (0.56) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL31006669 | 0.79 | SLC22A12 (0.56) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL22216857 | 0.78 | KDM4E (0.54) | KDM4EALDH1A1GLAGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023202623-A1 | POLQ INHIBITOR COMPOUND AND USE THEREOF | 南京再明医药有限公司 | 2023-10-26 | — | — | WO | disclosed |