Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 6/20 | 0.40 |
| ▸ | GSK3B | P49841 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL26600264 | 1.00 | HRH4 (0.45) | HRH4HRH3PIM1PIM3PIM2 | |
| SCHEMBL26669784 | 0.88 | PIM1 (0.45) | PIM1PIM3PIM2HTR2CGSK3B | |
| Trifluoroacetic Acid SCHEMBL26599770 | 0.76 | HRH4 (0.48) | HRH4HRH3PIM1PIM3PIM2 | |
| Trifluoroacetic Acid SCHEMBL26599759 | 0.76 | HRH4 (0.48) | HRH4HRH3PIM1PIM3PIM2 | |
| Trifluoroacetic Acid SCHEMBL5471477 | 0.76 | DPP4 (0.46) | HTR2CHTR2AKCNH2 | |
| SCHEMBL30609691 | 0.74 | HTR2C (0.46) | PIM1PIM3PIM2HTR2CGSK3B | |
| SCHEMBL17884953 | 0.74 | HTR2C (0.46) | PIM1PIM3PIM2HTR2CGSK3B | |
| Trifluoroacetic Acid SCHEMBL5633122 | 0.71 | PKM (0.40) | HTR2CGSK3BHTR2AHTR2B | |
| SCHEMBL15219155 | 0.71 | HTR2C (0.48) | PIM1PIM3PIM2HTR2CHTR2A | |
| Trifluoroacetic Acid SCHEMBL5631915 | 0.71 | PKM (0.40) | HTR2CGSK3BHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12454547-B2 | Steroidal compositions and methods of treating lipogenic cancers | Asteroid Therapeutics (US) | 2025-10-28 | — | — | US | disclosed |
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | Asteroid Therapeutics | 2023-10-26 | — | — | US | disclosed |
| WO-2023205801-A2 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | Asteroid Therapeutics (US) | 2023-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12454547-B2 | Steroidal compositions and methods of treating lipogenic cancers | SREBF1, SREBF2, NR1H3 | HRH4 4558/4885HRH3 4494/4885PIM1 3600/4885 |
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | SREBF1, SREBF2, NR1H3 | HRH4 4558/4885HRH3 4494/4885PIM1 3600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.