Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 11/20 | 0.54 |
| ▸ | TP53 | P04637 | 8/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26601281 | 1.00 | LMNA (0.54) | LMNATP53POLBRXFP1MAPT | |
| SCHEMBL26600944 | 0.87 | LMNA (0.53) | LMNATP53POLBRXFP1MAPT | |
| SCHEMBL26601186 | 0.85 | LMNA (0.70) | LMNATP53POLBRXFP1MAPT | |
| SCHEMBL26601455 | 0.84 | MAPT (0.74) | LMNATP53POLBMAPT | |
| SCHEMBL30670721 | 0.84 | MAPT (0.74) | LMNATP53POLBMAPT | |
| SCHEMBL26600788 | 0.84 | MAPT (0.74) | LMNATP53POLBMAPT | |
| SCHEMBL26601166 | 0.82 | LMNA (0.71) | LMNATP53POLBRXFP1MAPT | |
| SCHEMBL26601282 | 0.81 | MAPT (0.51) | LMNATP53POLBRXFP1MAPT | |
| SCHEMBL26601097 | 0.81 | LMNA (0.56) | LMNATP53POLBRXFP1MAPT | |
| SCHEMBL30670737 | 0.80 | LMNA (0.59) | LMNATP53POLBRXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205415-A1 | TRANSCRIPTION FACTOR EB ACTIVATORS AND USES THEREOF | MITOBRIDGE INC. (US) | 2023-10-26 | — | — | WO | disclosed |