Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449821 | 0.90 | ALDH1A1 (0.49) | SMN1; SMN2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL28615780 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTHPGDRAB9ANPC1 | |
| SCHEMBL9467823 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTHPGDRAB9ANPC1 | |
| SCHEMBL9467815 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTHPGDRAB9ANPC1 | |
| Potassium Ion SCHEMBL9467819 | 0.82 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL9539325 | 0.81 | ESR1 (0.55) | SMN1; SMN2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL31467341 | 0.80 | MAPT (0.43) | SMN1; SMN2MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL28895523 | 0.77 | ESR1 (0.44) | SMN1; SMN2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL2581993 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL28724952 | 0.75 | ALDH1A1 (0.40) | SMN1; SMN2MAPTWDR5ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205279-A1 | IMPROVED RAMAN SPECTROSCOPY WITH THE ADDITION OF AROMATIC COMPOUNDS | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-10-26 | — | — | WO | disclosed |
| WO-2023205280-A1 | ENHANCED FLUORESCENCE SIGNAL THROUGH THE APPLICATION OF AROMATIC ADDITIVES ONTO THE MICROSCOPY SAMPLE FOR STANDARD FLUORESCENCE, FLUORESCENCE MICROSCOPY AND COMBINED FLUORESCENCE MALDI MICROSCOPY/IMAGING | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-10-26 | — | — | WO | disclosed |