Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.34 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26601379 | 1.00 | KDM4E (0.42) | KDM4EALDH1A1ALOX15HSD17B10MEN1 | |
| SCHEMBL16616328 | 0.75 | MGAM (0.40) | KDM4EALDH1A1ALOX15HSD17B10MEN1 | |
| SCHEMBL26659825 | 0.75 | CYP2C9 (0.43) | KDM4EALDH1A1ALOX15HSD17B10MEN1 | |
| SCHEMBL26601076 | 0.73 | HPGD (0.41) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL26601074 | 0.73 | HPGD (0.41) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL28346823 | 0.72 | HPGD (0.44) | KDM4EALDH1A1ALOX15HSD17B10MEN1 | |
| SCHEMBL15206749 | 0.69 | MEN1 (0.43) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL15206750 | 0.69 | MEN1 (0.43) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL6052889 | 0.69 | HCAR2 (0.48) | KDM4EALDH1A1ALOX15HSD17B10MEN1 | |
| SCHEMBL30668508 | 0.69 | HCAR2 (0.48) | KDM4EALDH1A1ALOX15HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205415-A1 | TRANSCRIPTION FACTOR EB ACTIVATORS AND USES THEREOF | MITOBRIDGE INC. (US) | 2023-10-26 | — | — | WO | disclosed |