Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26601074 | 1.00 | HPGD (0.41) | HPGDMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL26645844 | 0.78 | KDM4E (0.52) | HPGDMEN1KMT2AALDH1A1POLB | |
| SCHEMBL28346823 | 0.76 | HPGD (0.44) | HPGDMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL70795 | 0.74 | SMN1; SMN2 (0.65) | HPGDMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL26601381 | 0.73 | KDM4E (0.42) | HPGDMEN1KMT2AALDH1A1GABRP | |
| SCHEMBL26601379 | 0.73 | KDM4E (0.42) | HPGDMEN1KMT2AALDH1A1GABRP | |
| SCHEMBL9491457 | 0.72 | SMN1; SMN2 (0.62) | HPGDMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL15206749 | 0.70 | MEN1 (0.43) | HPGDMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL15206750 | 0.70 | MEN1 (0.43) | HPGDMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9315436 | 0.67 | SMN1; SMN2 (0.50) | HPGDMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205415-A1 | TRANSCRIPTION FACTOR EB ACTIVATORS AND USES THEREOF | MITOBRIDGE INC. (US) | 2023-10-26 | — | — | WO | disclosed |