Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5964133 | 1.00 | IDO1 (0.38) | IDO1TDO2L3MBTL1GRIN2DGRIN3B | |
| SCHEMBL23824703 | 1.00 | IDO1 (0.38) | IDO1TDO2L3MBTL1GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL26601378 | 0.98 | IDO1 (0.38) | IDO1TDO2L3MBTL1GRIN2DGRIN3B | |
| SCHEMBL11269081 | 0.95 | GRIN2D (0.39) | IDO1TDO2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL11280209 | 0.94 | CCR2 (0.40) | IDO1TDO2GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL11261225 | 0.94 | GRIN2D (0.38) | IDO1TDO2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5964747 | 0.90 | IDO1 (0.40) | IDO1TDO2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL23824314 | 0.90 | IDO1 (0.40) | IDO1TDO2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL26448029 | 0.90 | IDO1 (0.40) | IDO1TDO2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1066359 | 0.90 | IDO1 (0.40) | IDO1TDO2GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969957-A | Indazole compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-10-31 | — | — | CN | disclosed |
| WO-2023205779-A1 | PROCESS FOR MAKING CYSTEINE PROTEASE INHIBITOR INTERMEDIATES | Pardes Biosciences, Inc. (US) | 2023-10-26 | — | — | WO | disclosed |
| CN-116685576-A | Cysteine protease inhibitors and methods of use thereof | 美商帕迪斯生物科学公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-116096714-A | Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections | 安力高医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |