Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31457364 | 0.91 | NPSR1 (0.47) | NPSR1TDP1MAPTATMMEN1 | |
| SCHEMBL31676238 | 0.89 | NPSR1 (0.46) | NPSR1TDP1MAPTATMMEN1 | |
| SCHEMBL26632733 | 0.81 | CNR2 (0.54) | KMT2AALDH1A1 | |
| SCHEMBL19982954 | 0.81 | TDP1 (0.53) | NPSR1TDP1MAPTATMMEN1 | |
| SCHEMBL19983040 | 0.80 | TDP1 (0.53) | NPSR1TDP1MAPTATMMEN1 | |
| SCHEMBL19983072 | 0.79 | TDP1 (0.53) | NPSR1TDP1MAPTATMMEN1 | |
| SCHEMBL12708216 | 0.77 | KCNA5 (0.46) | NPSR1TDP1MAPTATMMEN1 | |
| SCHEMBL21153191 | 0.77 | TDP1 (0.51) | NPSR1TDP1MAPTATMMEN1 | |
| SCHEMBL7545229 | 0.77 | TDP1 (0.52) | NPSR1TDP1MAPTATMMEN1 | |
| SCHEMBL7544858 | 0.77 | TDP1 (0.52) | NPSR1TDP1MAPTATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205219-A1 | PROTEOLYSIS TARGETING CHIMERA (PROTAC) COMPOSITIONS USING UBIQUITIN CONJUGATING ENZYME LIGANDS | BERG LLC (US) | 2023-10-26 | — | — | WO | disclosed |