Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31359467 | 1.00 | PARP1 (0.36) | PARP1CYP1A2ALDH1A1MAPTESR1 | |
| SCHEMBL31359451 | 0.74 | PARP1 (0.33) | PARP1ALDH1A1MAPTRAB9AKDM4E | |
| SCHEMBL26602716 | 0.74 | PARP1 (0.33) | PARP1ALDH1A1MAPTRAB9AKDM4E | |
| SCHEMBL30625273 | 0.73 | CYP1A2 (0.36) | CYP1A2ALDH1A1MAPTESR1ESR2 | |
| SCHEMBL26602827 | 0.73 | CYP1A2 (0.36) | CYP1A2ALDH1A1MAPTESR1ESR2 | |
| SCHEMBL29799635 | 0.69 | GRIN2D (0.42) | PARP1CYP1A2ALDH1A1ESR1ESR2 | |
| SCHEMBL27186626 | 0.69 | GRIN2D (0.42) | PARP1CYP1A2ALDH1A1ESR1ESR2 | |
| SCHEMBL31392493 | 0.69 | HPGD (0.36) | PARP1CYP1A2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL14013817 | 0.67 | POLB (0.36) | PARP1CYP1A2ALDH1A1RAB9ANPC1 | |
| SCHEMBL12190827 | 0.65 | KDM4E (0.38) | PARP1CYP1A2ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4511373-A1 | PI3K? INHIBITORS | Synnovation Therapeutics, Inc. (US) | 2025-02-26 | — | — | EP | disclosed |
| WO-2023205680-A1 | PI3Kα INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| WO-2023205680-A1 | PI3Kα INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |