Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26602802 | 1.00 | PARP1 (0.36) | PARP1CYP1A2ALDH1A1MAPTESR1 | |
| SCHEMBL31359451 | 0.74 | PARP1 (0.33) | PARP1ALDH1A1MAPTRAB9AKDM4E | |
| SCHEMBL26602716 | 0.74 | PARP1 (0.33) | PARP1ALDH1A1MAPTRAB9AKDM4E | |
| SCHEMBL30625273 | 0.73 | CYP1A2 (0.36) | CYP1A2ALDH1A1MAPTESR1ESR2 | |
| SCHEMBL26602827 | 0.73 | CYP1A2 (0.36) | CYP1A2ALDH1A1MAPTESR1ESR2 | |
| SCHEMBL29799635 | 0.69 | GRIN2D (0.42) | PARP1CYP1A2ALDH1A1ESR1ESR2 | |
| SCHEMBL27186626 | 0.69 | GRIN2D (0.42) | PARP1CYP1A2ALDH1A1ESR1ESR2 | |
| SCHEMBL31392493 | 0.69 | HPGD (0.36) | PARP1CYP1A2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL14013817 | 0.67 | POLB (0.36) | PARP1CYP1A2ALDH1A1RAB9ANPC1 | |
| SCHEMBL12190827 | 0.65 | KDM4E (0.38) | PARP1CYP1A2ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270213-A1 | PI3Ka INHIBITORS | PIKAVATION THERAPEUTICS, INC. | 2025-08-28 | — | — | US | disclosed |
| CN-119654321-A | PI3K alpha inhibitors | 突触活化疗法股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270213-A1 | PI3Ka INHIBITORS | PIK3CA, PIK3C2A, PIK3R5 | PARP1 1087/4885CYP1A2 4561/4885ALDH1A1 3839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.