Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30626165 | 1.00 | GAA (0.61) | GAAALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL26603319 | 0.91 | HIF1A (0.55) | GAASMN1; SMN2HIF1AUSP2PARG | |
| SCHEMBL30709107 | 0.91 | HIF1A (0.55) | GAASMN1; SMN2HIF1AUSP2PARG | |
| SCHEMBL30626167 | 0.90 | GAA (0.59) | GAAALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL26603363 | 0.90 | GAA (0.59) | GAAALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL30709142 | 0.89 | ALDH1A1 (0.68) | GAAALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL26603443 | 0.89 | ALDH1A1 (0.68) | GAAALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL30709104 | 0.88 | GAA (0.63) | GAAALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL26603248 | 0.88 | GAA (0.63) | GAAALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL30709106 | 0.86 | GAA (0.64) | GAAALDH1A1HPGDHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023202582-A1 | GPCR REGULATOR AND USE THEREOF | 北京昌平实验室 | 2023-10-26 | — | — | WO | disclosed |