Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 15/20 | 0.55 |
| ▸ | PARG | Q86W56 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30709126 | 0.92 | PARG (0.57) | HIF1APARGGAAUSP2LMNA | |
| SCHEMBL26603305 | 0.92 | PARG (0.57) | HIF1APARGGAAUSP2LMNA | |
| SCHEMBL26603363 | 0.91 | GAA (0.59) | HIF1AGAAUSP2SMN1; SMN2 | |
| SCHEMBL30709107 | 0.91 | HIF1A (0.55) | HIF1APARGGAAUSP2LMNA | |
| SCHEMBL26603319 | 0.91 | HIF1A (0.55) | HIF1APARGGAAUSP2LMNA | |
| SCHEMBL30626167 | 0.91 | GAA (0.59) | HIF1AGAAUSP2SMN1; SMN2 | |
| SCHEMBL26603399 | 0.88 | HIF1A (0.67) | HIF1APARGGAAUSP2LMNA | |
| SCHEMBL26603266 | 0.88 | PARG (0.57) | HIF1APARGGAAUSP2LMNA | |
| SCHEMBL30709059 | 0.88 | PARG (0.57) | HIF1APARGGAAUSP2LMNA | |
| SCHEMBL30709172 | 0.88 | PARG (0.53) | HIF1APARGGAAUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023202582-A1 | GPCR REGULATOR AND USE THEREOF | 北京昌平实验室 | 2023-10-26 | — | — | WO | disclosed |